Extended value proposition by Skyepharma
In a process of continuous improvement, we are challenging ourselves every day to achieve optimal product quality for our customers. Particle size reduction by grinding, after granulation process, is often necessary to meet the strict specifications required by our clients.
Why has Skyepharma invested in high quality Frewitt equipment?
In the context of an industrial transfer project for a client, we needed to expand our equipment fleet with the addition of a Frewitt Hammer Mill.
Hammer mill FlexMill HW-3 is a grinding equipment widely used in the pharmaceutical industry, notably because its granule homogenizing action facilitates the filling of capsules. This has a direct impact on the product manufacturing duration by avoiding potential difficulties during the capsule filling phase. Most importantly, this new equipment offers an advantageous value proposition in terms of time-to-market, and successful first time, tech transfer exercise, thus guaranteeing the customer a high-quality product delivered on time.
A better size particle distribution
FlexMill HW-3 can perform a size reduction at a speed up to 7000 rpm. Its technical mechanical design allow us to micronize both active ingredients or excipients.
The powder is pulverized in the Hammer Mill’s high-speed rotating blades. Very fines particles (0.2 mm) are produced while they are ground through the milling chamber. The chamber was designed following current GMP guidelines, in accordance with our standards. It’s a seamless monobloc design, allowing us to avoid risk cross contamination.
Several accessorial, technological modules are proposed by our manufacturer Frewitt, which can be used on other projects for pharmaceutical powder processing.
We have transformed the needs of our customers into a tailor-made equipment
To meet the specific needs of our customer, we adapted the hammer mill FlexMill HW-3 from Frewitt to replace the original oven drying system by fluidized bed technology.
Consequentially, this upgrade gives several advantages while respecting the particle’s physico-chemical properties, such as :
High rates of moisture removal due to an excellent gas-particle constant,
Reduced time for drying
Lower capital and maintenance costs
An energy consumption reduced and a yield increased
The outcome of a successful collaboration
The collaboration between our historical manufacturer Frewitt and Skyepharma to carry out these improvements, and the industrial transfer project has been very effective.
Our operational industrial process skills combined with those of our Pharmaceutical development team enabled us to respond favorably and with a reactivity praised by our customer.
Congratulations to the whole Skyepharma team for taking up this challenge. TEAM IS NUMBER ONE.
Jean – René, Production Supervisor
Contact us at this following address if you have any project: partnership@skyepharma.com.